Serena Dudek

Transcriptional Regulation by Neuronal Activity: To the Nucleus and Back Serena Dudek

Marc Notes: Includes bibliographical references and index. Table of Contents: Part I. Activity-regulated Transcription: Getting to the Nucleus -- 1. Transcriptional Regulation of Activity-Dependent Genes by Birdsong / Tarciso A. F. Velho, Claudio V. Mello -- 2. To the Nucleus with Proteomics / Bryen A. Jordan, Edward B. Ziff -- 3. Transcriptional Regulation of the Tbr1-CASK-CINAP Protein Complex in Response to Neuronal Activity / Yi-Ping Hsueh -- 4. Intracellular Calcium Waves Transmit Synaptic Information to the Nucleus in Hippocampal Pyramidal Neurons / Mark F. Yeckel, Amanda A. Sleeper, John S. Fitzpatrick, Daniel N. Hertle, Anna M. Hagenston, Robin T. Garner -- 5. Role of Action Potentials in Regulating Gene Transcription: Relevance to LTP / J. Paige Adams, Rachel A. Robinson, Serena M. Dudek -- 6. L-type Channel Regulation of Gene Expression / Natalia Gomez-Ospina, Ricardo Dolmetsch -- Part II. Activity-regulated Transcription: Gene Regulation -- 7. CREB-Dependent Transcription and Synaptic Plasticity / Angel Barco, Dragana Jancic, Eric R. Kandel -- 8. Activity-Dependent Regulation of Brain-derived neurotrophic factor Transcription / Anne E. West -- 9. Role of Signal-responsive Class IIa Histone Deacetylases in Regulating Neuronal Activity-dependent Gene Expression / Brian Yee Hong Lam, Sangeeta Chawla -- 10. NFAT-Dependent Gene Expression in the Nervous System: A Critical Mediator of Neurotrophin-Induced Plasticity / Rachel D. Groth, Paul G. Mermelstein -- 11. Activity-Dependent Bigenomic Transcriptional Regulation of Cytochrome c Oxidase in Neurons / Margaret T. T. Wong-Riley, Huan Ling Liang, Sakkapol Ongwijitwat -- 12. Not Just for Muscle Anymore: Activity and Calcium Regulation of MEF2-Dependent Transcription in Neuronal Survival and Differentiation / Aryaman Shalizi, Azad Bonni -- Part III. Activity-regulated Transcription: Role in Nervous System Function -- 13. Synaptic Growth and Transcriptional Regulation in Drosophila / Cynthia Barber, J. Troy Littleton -- 14. MMP-9/TIMP-1 Extracellular Proteolytic System as AP-1 Target in Response to Neuronal Activity / Grzegorz M. Wilczynski, Leszek Kaczmarek -- 15. Activity-dependent Gene Transcription in Neurons: Defining the Plasticity Transcriptome / Alison L. Barth, Lina Yassin -- 16. Transcriptional Mechanisms Underlying the Mammalian Circadian Clock / Hai-Ying Mary Cheng, Karl Obrietan -- 17. Intersecting Genetics with Lifestyle: the Role of Exercise and Diet in Synaptic Plasticity and Cognitive Enhancement / Fernando Gomez-Pinilla, Shoshanna Vaynman -- 18. CREB Responsive Transcription and Memory Formation / Thomas C. Tubon, Jerry C. P. Yin -- 19. Dynamic Transcription of the Immediate-Early Gene Arc in Hippocampal Neuronal Networks: Insights into the Molecular and Cellular Bases of Memory Formation / John F. Guzowski, Ting Nie, Teiko Miyashita -- Index. Jacket Description/Back: Regulation of gene transcription by neuronal activity is evident in a large number of neuronal processes ranging from neural development and refinement of neuronal connections to learning and response to injury. In the field of activity-dependent gene expression, rapid progress is being made that can impact these, and many other areas of neuroscience. The major aim of Transcriptional Regulation by Neuronal Activity: To the Nucleus and Back is to illustrate key advances in the field specifically how signals are transmitted to the nucleus in response to neuronal activity, what genes are activated and how this is achieved, and how these changes in gene expression alter neuronal function. About the Author: Serena M. Dudek, Ph. D. is best known for her seminal work describing Long-term synaptic Depression (LTD) in the hippocampus. Dr. Dudek heads the Synaptic and Developmental Plasticity Group at the National Institute of Environmental Health Sciences, where her laboratory studies the cellular mechanisms of synaptic plasticity in the adult and developing mammalian brain. Although once a critic of the proposed necessity of transcription for maintenance of synaptic plasticity, Dr. Dudek now devotes much of her time to work on the topic. "Description for Sales People: The regulation of gene transcription by neuronal activity is evident in many neuronal processes, ranging from neural development and refinement of neuronal connections to learning and response to injury. This book illustrates key advances in the field of activity regulation of gene transcription. Specifically, it explores how signals are transmitted to the nucleus in response to neuronal activity, which genes are activated and how they are activated, and how these changes in gene expression alter neuronal function. The editor and authors cover a variety of methods and topics, including signal initiation and transduction to the nucleus and possible functions of the activity-regulated genes. Publisher Marketing: 'Transcriptional Regulation by Neuronal Activity' illustrates key advances in the field - specifically how signals are transmitted to the nucleus in response to neuronal activity, what genes are activated and how this is achieved, and how these changes in gene expression alter neuronal function.