Molecular Mechanisms of Neuronal Responsiveness - Advances in Experimental Medicine and Biology - Yigal H. Ehrlich - Libros - Springer-Verlag New York Inc. - 9781468476200 - 18 de mayo de 2012
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Yigal H. Ehrlich
Molecular Mechanisms of Neuronal Responsiveness - Advances in Experimental Medicine and Biology Softcover reprint of the original 1st ed. 1987 edition

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The interaction of neurotransmitters, neuromodulators and neuroactive drugs with receptors localized at the cell surface initiates a chain of molecular events leading to integrated neuronal responses to the triggering stimuli. Major advancements in the characterization and isolation of recep­ tor molecules have answered many quest ions regarding the nature of the ele­ ments that determine the specificity in these interactions. At the same time, recent studies have provided evidence that delicate regulation by intracellular enzymatic systems determines the efficiency of the stimulus­ response coupling process, mediates the interaction between receptors, operates in feedback control mechanisms and transduces signals from the receptors to various effector sites in a highly coordinated fashion. These studies are at the focus of the present volume, which is an outcome of a symposium held at the University of Vermont College of Medicine on March 21-23, 1986, in conjunction with the seventeenth annual meeting of the Amer­ ican Society for Neurochemistry. The symposium has demonstrated clearly that the concerted efforts of investigators in neurophysiology, biochemis­ try, pharmacology, cell-biology, molecular genetics, neurology, and psy­ chiatry are required to achieve better understanding of the processes under­ lying neuronal responsiveness. This volume includes contributions provided by prominent investigators in all these research areas. We hope that the readers will find here a useful source of information and ideas for stimu­ lating further studies which may serve to narrow the gap between basic neuroscience research and its clinical implications.

563 pages, 107 black & white illustrations, biography

Medios de comunicación Libros     Paperback Book   (Libro con tapa blanda y lomo encolado)
Publicado 18 de mayo de 2012
ISBN13 9781468476200
Editores Springer-Verlag New York Inc.
Páginas 563
Dimensiones 178 × 254 × 30 mm   ·   984 g
Lengua Inglés  

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