Ashwini Mohite

Screening of Bioflavonoid Morin: Its Burn, Would Healing, Hepatoprotective and Antidiabetic Activities in Rat Ashwini Mohite

In the present study adult male wistar rats weighing 150 -200 g at the start of experiment were used and for diabetes 200-250g weighing rats were taken. They were employed for the evaluation of hepatoprtoection; burn wound healing and antidiabetic activity by treating with bioflavonoid Morin hepatoprotectivity. Hepatotoxicity is induced by Rifampicin Isoniazid- Drug was administered for 15 days. After the treatment, blood collected from tail vein and was examined for the levels of AST, ALT, Total Protein, and Direct Bilirubin and also screened for histopathological studies. Hepatotoxicity induced by Thioacetamide- Hepatotoxicity induced by Thioacetamide by administration for three consecutive days and after three days treatment, blood collected from tail vein and examined for the levels of AST, ALT, T Protein Bilirubin and also screened for histopathological examination. Burn wound healing activity: Burn wound was induced by water at 900C using 300mm2 diameter of mould, on the back of the male wistar albino rats. The drugs were administered to the animals up to healing. Wound contraction 50%, re-epithelialization parameters were studied. Antidiabetic activity: 200-250g weighing alb