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An Efficient Pyrimidine Scaffolds Against Bacterial Strains: Pyrimidine Derivatives Silveira Karyn Valzita
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An Efficient Pyrimidine Scaffolds Against Bacterial Strains: Pyrimidine Derivatives
Silveira Karyn Valzita
A series of novel 2-(substituted benzylidene)-7-(4-bromophenyl)-5-(furan-2-yl)-2H-thiazolo[3,2-a]pyrimidin-3(7H)-ones were synthesized by using established methods and were characterized by IR, 1H NMR and Mass spectroscopy in order to confirm their formation. These compounds were synthesized to evaluate their antitubercular, antibacterial and antifungal potency. Docking studies revealed the importance of functional groups and its different biological action. They were found to be potent against Mycobacterium tuberculosis H37Ra strain, also potent against Gram +ve, Gram ?ve and fungal strains
| Medios de comunicación | Libros Paperback Book (Libro con tapa blanda y lomo encolado) |
| Publicado | 12 de julio de 2013 |
| ISBN13 | 9783659428517 |
| Editores | LAP LAMBERT Academic Publishing |
| Páginas | 168 |
| Dimensiones | 150 × 10 × 225 mm · 268 g |
| Lengua | Alemán |