Oleg Batishchev

Bioelektrokhimiya Bisloynykh Lipidnykh Membran, Ne Soderzhashchikh Rastvoritel': Issledovanie Protsessa Polucheniya, a Takzhe Svoystv Bisloynykh ... Rastvoritel' Oleg Batishchev Russian edition

Dannaya monografiya posvyashchena aktual'noy probleme sozdaniya bisloynykh lipidnykh membran (BLM), ne soderzhashchikh rastvoritel', i issledovaniyu ikh svoystv. V rabote predstavleny razrabotannye avtorom metodiki alkilirovaniya stekol, pozvolivshie sformirovat' BLM, polnost'yu lishennye rastvoritelya. Issledovany effekty izmeneniya poverkhnostnykh svoystv ispol'zuemogo lipida i ikh vliyanie na protsess formirovaniya bisloev. Pokazano, chto sushchestvennoe vliyanie na protsess polucheniya membran metodom svedeniya monosloev okazyvayut spetsificheskaya adsorbtsiya ionov i gidratatsiya polyarnykh grupp lipidov, vliyayushchaya na mekhanicheskie parametry lipidnykh monosloya i bisloya. Razrabotan metod rascheta zavisimosti natyazheniya BLM ot rN. Predstavlennaya metodika formirovaniya lipidnykh membran, ne soderzhashchikh rastvoritel', mozhet byt' primenena dlya modelirovaniya i analiza mnogikh membrannykh yavleniy, takikh, kak protsessy sliyaniya i deleniya membran, transporta ionov cherez kanaly, obrazovanie domenov v lipidnom bisloe i tak dalee. Obnaruzhennyy v rabote effekt izmeneniya natyazhenie lipidnykh monosloev i bisloev v oblasti fiziologicheskikh znacheniy rN sredy vazhen dlya opisaniya razlichnykh protsessov funktsionirovaniya kletochnykh membran.