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Possible Mechanisms of Methylmercury Neurotoxicity: Correlation Between the Metabolic Effects of Methylmercury and 5-oxoprolinease Inhibitor on Both C6 Glial Cells and Pc12 Ezzat Awad
Possible Mechanisms of Methylmercury Neurotoxicity: Correlation Between the Metabolic Effects of Methylmercury and 5-oxoprolinease Inhibitor on Both C6 Glial Cells and Pc12
Ezzat Awad
Different studies reported that glutathione (GSH) play a major role in modulating methylmercury (MeHg) neurotoxicity. Glutathione synthetase deficiency (GSD) and 5- Oxoprolinase deficiencies are two inborn errors of GSH metabolism; which were associated with physiological and pathological features resembling patients with Minamata disease (MD). The present study aimed to investigate whether there are similarities between the metabolic effects of MeHg and 5-oxoprolinase inhibitor (ICA) on both C6 Glial cells and PC12 neurons.
| Medios de comunicación | Libros Paperback Book (Libro con tapa blanda y lomo encolado) |
| Publicado | 15 de junio de 2012 |
| ISBN13 | 9783846585504 |
| Editores | LAP LAMBERT Academic Publishing |
| Páginas | 104 |
| Dimensiones | 150 × 6 × 226 mm · 173 g |
| Lengua | Alemán |